| ncRNA name | PEDF siRNA |
| ncRNA Category | siRNA |
| Disease name | diabetic retinopathy (DR) |
| Species | Rattus norvegicus |
| Tissues/Cell_line | rat Müller cell line rMC-1 |
| Methods | Western blot, ELISA, immunohistochemistry, siRNA transfection, immunostaining |
| Expression pattern | associated |
| Functional description | PEDF is a endogenous anti-inflammatory factor in the eye. Down-regulation of PEDF expression by siRNA resulted in significantly increases of VEGF and TNF-alpha secretion in retinal Müller cells. |
| PubMed ID | 16368716 |
| Year | 2006 |
| Title | Pigment epithelium-derived factor (PEDF) is an endogenous antiinflammatory factor. |
| Drug-related ncRNA | NO |
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